书目名称 | Laser Desorption Ionization Mass Spectrometry Based on Nanophotonic Structure: From Material Design |
编辑 | Moon-Ju Kim |
视频video | |
概述 | Presents multiple strategies and design rules of nanophotonic structures for high LDI-MS performance.Contains proof-of-concept studies of nanostructure-based effective detection of low-polarity.Provid |
丛书名称 | Springer Theses |
图书封面 |  |
描述 | This book presents innovative laser desorption ionization (LDI)-active nanophotonic structures for addressing the challenges that matrix-assisted laser desorption ionization mass spectrometry (MALDI-MS) is currently facing and for enhancing LDI efficiency. It presents a variety of cutting-edge nanophotonic structures to satisfy the mass-analytical needs of sensitivity, reproducibility, and quantification. As opposed to the commercialized, conventional organic matrix used in MALDI-MS, these nanostructures are validated to be highly effective in detecting small metabolites and drugs, highlighting their considerable potential in the mass spectrometry field. It also systematically elucidates fundamental LDI processes in terms of the photo-thermal, electronic, and structural characteristics of nanophotonic structures, offering mechanistic knowledge of LDI-MS. Even though LDI-MS performance is heavily influenced by a number of nanostructure parameters, relatively little is known about the LDI processes associated with those characteristics. An in-depth understanding of nanostructure characteristics and LDI mechanisms thus paves the way for more effective, rational design and development |
出版日期 | Book 2023 |
关键词 | LDI-MS; High Sensitivity and Quantification; Nanophotonic Structure; Metal-Semiconductor Nanohybrid; The |
版次 | 1 |
doi | https://doi.org/10.1007/978-981-99-6878-7 |
isbn_softcover | 978-981-99-6880-0 |
isbn_ebook | 978-981-99-6878-7Series ISSN 2190-5053 Series E-ISSN 2190-5061 |
issn_series | 2190-5053 |
copyright | The Editor(s) (if applicable) and The Author(s), under exclusive license to Springer Nature Singapor |