| 书目名称 | Large-Scale Optimization with Applications |
| 副标题 | Part III: Molecular |
| 编辑 | Lorenz T. Biegler,Andrew R. Conn,Fadil N. Santosa |
| 视频video | |
| 丛书名称 | The IMA Volumes in Mathematics and its Applications |
| 图书封面 |  |
| 描述 | Many important molecular conformation problems, such as protein folding, are expressed as global minimization problems. It is the fact that local minimization is insufficient, that markedly differentiates this volume from the previous two. Unfortunately, global minimization problems that result from models of molecular conformation are usually intractable. For example, simple 1-dimensional versions of distance conformation problems are NP-hard. Nevertheless, there has been significant recent progress in the design of promising heuristic strategies (often involving the use of high- performance parallel computers) for computing approximate global minimizers. The purpose of the sessions represented in this volume was to discuss the new algorithmic advances for global minimization in the context of protein folding and related molecular minimization problems. Emphasis was on practical shortcomings of current approaches, outstanding problems and questions, and the use of high-performance parallel computers. |
| 出版日期 | Book 1997 |
| 关键词 | Optimization algorithm; Optimization algorithms; algorithm; algorithms; chemical engineering; control; dif |
| 版次 | 1 |
| doi | https://doi.org/10.1007/978-1-4612-0693-4 |
| isbn_softcover | 978-1-4612-6870-3 |
| isbn_ebook | 978-1-4612-0693-4Series ISSN 0940-6573 Series E-ISSN 2198-3224 |
| issn_series | 0940-6573 |
| copyright | Springer Science+Business Media New York 1997 |
发表于 2025-3-21 19:03:44
