Titlebook: Lacrimal Gland, Tear Film, and Dry Eye Syndromes 2; Basic Science and Cl David A. Sullivan,Darlene A. Dartt,Michele A. Mene Book 1998 The E

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A Clinician Looks at the Tearfilm glands and the ocular surface, the causes of dry eye, and new treatments. Remember, the reason we are pursuing this knowledge is to help those who suffer from dry eye, our patients, and, perhaps, someday offer a cure for each of the different types of dry eye.

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Aberrant Lacrimal Gland Development in an Anophthalmic Mutant Strain of Rat is also known to result as a teratogenic effect of drugs.. Such teratogenic anophthalmia reported for laboratory rats was found to be bilateral as well as unilateral.. Our institution has recently isolated a strain of mutant anophthalmic rats that were derived from a parent colony of inbred CFY rats..

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Studies of Ligand Binding and CD Analysis with Apo- and Holo-Tear Lipocalinsipid molecules.. Cholesterol, fatty acids, phospholipids, and glycolipids are bound to TL in tears. TL are promiscuous and have been shown to bind retinol, synthetic analogs of cholesterol, fatty acids, fatty alcohols, phospholipids, glycolipids, and even environmental contaminants such as dioctyl phthalate..

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Dinucleotide Repeat Polymorphism Near the Tear Lipocalin Geneid not use the gene symbol LCN1. These data together also definitively proved that LCN1 is not assigned to chromosome 8, as erroneously reported by Redl’s team.. We describe a dinucleotide polymorphism in the 3’ region of the tear lipocalin gene, which is known to span 6.2 kb and contains 7 exons..