| 书目名称 | Label-free and Multi-parametric Monitoring of Cell-based Assays with Substrate-embedded Sensors |
| 编辑 | Maximilian Oberleitner |
| 视频video | |
| 概述 | Doctoral thesis nominated as an outstanding PhD thesis by the University of Regensburg, Germany.Describes novel sensors for obtaining dynamic cell response information.Applies a variety of analytical |
| 丛书名称 | Springer Theses |
| 图书封面 |  |
| 描述 | This thesis describes novel substrate embedded physical sensors that can be used to monitor different types of cell-based assays non-invasively and label-free. The sensors described provide integrative information of the cells under study with an adaptable time resolution (ranging from milliseconds to days). This information about the dynamic cell response to chemical, physical or biological stimuli defines a new paradigm in fundamental biomedical research..The author, Maximilian Oberleitner, describes approaches in which the cells are directly grown on different sensor surfaces (gold-film electrodes, shear wave resonators or dye-doped polymer films). This approach, with the reacting cells in particularly close proximity and contact with the sensor surface, is key to a remarkable sensitivity, opening the way for a variety of new applications. This thesis not only introduces the fundamentals of each approach, but it also describes in great detail the design.principles and elucidates the boundary conditions of the new sensors.. |
| 出版日期 | Book 2018 |
| 关键词 | Cell-based assays; Label-free high-content sensing; Quartz crystal microbalance; Impedance spectroscopy |
| 版次 | 1 |
| doi | https://doi.org/10.1007/978-3-319-45384-2 |
| isbn_softcover | 978-3-319-83279-1 |
| isbn_ebook | 978-3-319-45384-2Series ISSN 2190-5053 Series E-ISSN 2190-5061 |
| issn_series | 2190-5053 |
| copyright | The Editor(s) (if applicable) and The Author(s), under exclusive license to Springer Nature Switzerl |
发表于 2025-3-21 19:08:17
