Titlebook: Klinische Urologie; Vom Befund zur Thera Stephan Roth,Burkhard Ubrig,Peter Rathert Book 2001Latest edition Springer-Verlag Berlin Heidelber

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Book 2001Latest editionnd und nicht das übergeordnete Krankheitsbild gewählt wurden, können klinische Probleme der täglichen Praxis effektiv gelöst und schnell rekapituliert werden. Unflexible und oft unübersichtliche Flußdiagramme wurden durch komprimierte Informationsabfolgen ersetzt, die der klinischen Realität entspre

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.) gene. Genealogical and genetic studies have demonstrated that these families share a common founder more than 400 years ago. The mean age of onset of AD in these families is 45.2 years but the range is almost 30 years (35–62 years). The wide range in age of onset suggests that genetic and/or envi

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nts who carry PSEN mutations and have Alzheimer‘s disease with a variety of other clinical phenotypes including spastic paraplegia, seizures, myoclonus, parkinsonism, epilepsy and amyloid angiopathy. Remarkably, three of the studied families have frontotemporal dementia (FTD). The mutations associat

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Stephan Roth Prof. Dr. med.,Burkhard Ubrig Dr. med.,Axel Semjonow Dr. med.,Peter Rathert Prof. Dr. m tau (.) located at chromosome 17q21. Neuropathologically, these patients are characterized by tau-positive depositions in brain. However, autosomal dominant forms of FTD without . mutations have been reported, suggesting other tauopathy-related genetic defects. One such form is FTD linked to 17q21,

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Stephan Roth Prof. Dr. med.,Burkhard Ubrig Dr. med.,Axel Semjonow Dr. med.,Peter Rathert Prof. Dr. mng that phenotype to known disease mechanisms, including genetic variations and pathology. This approach has been particularly difficult with frontotemporal dementias (FTD), because of the diversity and continuous evolution of its behavioral, language and cognitive symptoms. Recent systematic clinic

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Stephan Roth Prof. Dr. med.,Burkhard Ubrig Dr. med.,Axel Semjonow Dr. med.,Peter Rathert Prof. Dr. mns a powerful approach for discovering the causal genes underlying phenotypes. For genetic mapping, the process of genotyping was previously a major rate-limiting step. Modern sequencing technology has greatly improved the resolution and speed of genetic mapping by reducing the time, labor, and cost

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rvorgerufen. Fragen nach einer Erklärung des Holocaust durch eine besondere Mentalität der Deutschen werden neu gestellt und häufig im Rahmen einer kulturalistischen Perspektive behandelt, die eine historisch konstante antisemitische Struktur in der deutschen Identität hervorhebt. Die folgenden Über