| 书目名称 | Kinase Inhibitors |
| 副标题 | Methods and Protocol |
| 编辑 | Bernhard Kuster |
| 视频video | |
| 概述 | Includes cutting-edge methods and protocols.Provides step-by-step detail essential for reproducible results.Contains key notes and implementation advice from the experts.Includes supplementary materia |
| 丛书名称 | Methods in Molecular Biology |
| 图书封面 |  |
| 描述 | .Protein and lipid kinases are often the master regulators of cell signaling in eukaryotic systems. The human genome codes for more than 500 of these enzymes and their misregulation has been shown to be involved in the onset and progression of many diseases including cancer and inflammation. Therefore, small molecule kinase inhibitors have become important research tools for the elucidation of the many biological roles of kinases and their mechanisms of action. Kinase inhibitors thus also contribute significantly to the drug pipelines of the pharmaceutical and biotechnology industries and to the growing need to treat cancer and inflammation. In .Kinase Inhibitors: Methods and Protocols., experts in kinase biology, drug discovery, and clinical research present a series of exemplary methods that can be used to address the many challenges facing scientists in the discovery and development of kinase inhibitors both for research and clinical use. Written in the highly successful .Methods in Molecular Biology™. series format, chapters contain introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, a |
| 出版日期 | Book 2012 |
| 关键词 | biochemical kinase activity assays; cancer; inflammation; lipid kinases; peptide substrates; protein kina |
| 版次 | 1 |
| doi | https://doi.org/10.1007/978-1-61779-337-0 |
| isbn_softcover | 978-1-4939-5757-6 |
| isbn_ebook | 978-1-61779-337-0Series ISSN 1064-3745 Series E-ISSN 1940-6029 |
| issn_series | 1064-3745 |
| copyright | Springer Science+Business Media, LLC 2012 |
发表于 2025-3-21 18:40:59
