Titlebook: Kainate Receptors; Novel Signaling Insi Antonio Rodríguez-Moreno,Talvinder S. Sihra Book 2011 The Editor(s) (if applicable) and The Author(

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https://doi.org/10.1007/978-1-4419-9557-5KAR; Kainate; Receptor; Rodríguez‑Moreno; Signaling

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The Editor(s) (if applicable) and The Author(s), under exclusive license to Springer Science+Busines

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In the Developing Hippocampus Kainate Receptors Control the Release of GABA from Mossy Fiber Termin pharmacological properties. In the hippocampus, KARs expressed at postsynaptic sites mediate a small component of excitatory postsynaptic currents while at presynaptic sites they exert a powerful control on transmitter release at both excitatory and inhibitory connections. KARs are developmentally

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Localization and Functions of Kainate Receptors in the Basal Ganglia,tsynaptically throughout the brain. Thus, kainate receptor activation mediates a large variety of pre- and postsynaptic effects on either glutamatergic or GABAergic synaptic transmission. Although ionotropic functions for KAR have been described in multiple brain regions, there is considerable evide

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Metabotropic Actions of Kainate Receptors in the Control of Glutamate Release in the Hippocampus,nd AMPA receptors), but functionally often purport examples of a metabotropic mode of operation. In the present chapter, we describe these metabotropic roles of KARs in the modulation of glutamate release in the hippocampus at CA3 Schaffer Collateral (SC)-CA1 Pyramidal Cell (PC) synapses and dentate

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