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Titlebook: Judah Folkman; A Biography Domenico Ribatti Book 2018 Springer International Publishing AG, part of Springer Nature 2018 angiogenesis.anti-

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发表于 2025-3-21 17:49:34 | 显示全部楼层 |阅读模式
书目名称Judah Folkman
副标题A Biography
编辑Domenico Ribatti
视频video
概述Judah Folkman is recognized as the modern father of angiogenesis research worldwide.Folkman isolated the first tumor angiogenesis factor (TAF).From 1980 to 2005, Folkman’s laboratory reported the disc
图书封面Titlebook: Judah Folkman; A Biography Domenico Ribatti Book 2018 Springer International Publishing AG, part of Springer Nature 2018 angiogenesis.anti-
描述.The aim if this book is to analyze the scientific biography of Judah Folkman, one of the most important scientist of the last century. More 50 years ago, Folkman found a revolutionary new way to think about cancer. Blood supply, Folkman hypothesized, was the key to tumor growth. Without new blood vessels, tumors simply did not thrive. In 1971, Folkman published his theory of angiogenesis in the “New England Journal of Medicine”. Angiogenesis, the formation and recruitment of new blood vessels, is necessary for tumor growth.  Critics of the theory were silenced over time as Folkman and his colleagues reported the first purified angiogenic molecule, the first angiogenesis inhibitor and proposed the concept of angiogenic disease. The mechanism of angiogenesis is now a worldwide field of investigation. Over the years, Folkman and a growing team of researchers have isolated the proteins and unraveled the processes that regulate angiogenesis. Meanwhile, a new generation of angiogenesis research has emerged as well, widening the field into new areas of human disease and deepening it to examine the underlying biological processes responsible for those diseases. .
出版日期Book 2018
关键词angiogenesis; anti-angiogenesis; history of medicine; tumor growth; vascular biology
版次1
doihttps://doi.org/10.1007/978-3-319-92633-9
isbn_softcover978-3-030-06476-1
isbn_ebook978-3-319-92633-9
copyrightSpringer International Publishing AG, part of Springer Nature 2018
The information of publication is updating

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发表于 2025-3-21 23:55:43 | 显示全部楼层
Development of Assays to Study Angiogenesis,anted in the rabbit ear (Sandison 1924). This enabled direct observation of the formation of new blood vessels in a healing wound. Folkman work started with perfused organs and then moved ., first using the rat air sac model (Folkman et al. 1963, 1971). As he said: “The phenomenon of angiogenesis wa
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Anti-angiogenesis, that: “it seems appropriate to speculate that ‘anti-angiogenesis’ may provide a form of cancer therapy worthy os serious exploration. One approach to the initiation of ‘anti-angiogenesis’ would be the production of an antibody against TAF; such an attempt is under way in our laboratory (…) Anti-ang
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Concluding Remarks,. In 2008, Robert Kerbel dedicated a review article published in the “New England Journal of Medicine” to the memory of Judah Folkman: “mentor, friend, and colleague, whose visionary hypothesis and numerous pioneering discoveries opened up and advanced the field of tumor angiogenesis and anti-angiog
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Domenico Ribattiction - cilities and factories. It addresses planning methods and procedures for various types of production facility up to and including entire factories, and is aimed at practicing factory planners and students alike. The book provides facts and demonstrates practical processes using case studies
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Domenico Ribattiorking in both areas have in cornrnon the study of the process in HEARING, yet different scientific areas always tend to diverge. A SYMPOSIUM ON PSY­ CHOPHYSICAL MODELS AND PHYSIOLOGICAL FACTS IN HEARING was or­ ganized for the exchange of information and to stimulate dis­ cussion between research w
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