Titlebook: JIMD Reports, Volume 42; Eva Morava,Matthias Baumgartner,Verena Peters Book 2018 Society for the Study of Inborn Errors of Metabolism (SSI

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Beneficial Effect of BH, Treatment in a 15-Year-Old Boy with Biallelic Mutations in ,nt was initiated early in life. We report on a 15-year-old boy with HPA due to a homozygous deletion in . in whom – despite his advanced age – treatment was initiated...: A boy with developmental delay, an extrapyramidal movement disorder, and persistently elevated plasma phenylalanine levels was di

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Secondary Hemophagocytic Syndrome Associated with COG6 Gene Defect: Report and Review,ated macrophages and T-lymphocytes. Clinically, it is characterized by prolonged fever, hepatosplenomegaly, hypertriglyceridemia, hypofibrinogenemia, pancytopenia, and hemophagocytosis in the bone marrow, spleen, or lymph nodes. It can be classified as primary if it is due to a genetic defect, or se

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lutionary programming, evolution strategies, and genetic programming. The text is a survey of some application of evolutionary algorithms. It introduces mutation, crossover, design issues of selection and replacement methods, the issue of populations size, and the question of design of the fitness f

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E. Rivers,B. C. Reynolds,S. Bunn,N. J. Leech,J. Straker,H. J. Lambertlutionary programming, evolution strategies, and genetic programming. The text is a survey of some application of evolutionary algorithms. It introduces mutation, crossover, design issues of selection and replacement methods, the issue of populations size, and the question of design of the fitness f

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Kenneth I. Berger,Barbara K. Burton,Gregory D. Lewis,Mark Tarnopolsky,Paul R. Harmatz,John J. Mitcheh problem (SPP) with a delay constraint on the total “cost” of the optimal path. The proposed algorithm uses the principle of Lagrange relaxation based aggregated cost, where PSO and noising metaheuristic are used for minimizing the modified cost function. It essentially consists of two PSOs. The ma

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Maureen Evans,Kay Nguo,Avihu Boneh,Helen Trubyinventory levels at the same time. The IRP is notable for its difficulty - even finding feasible initial solutions poses a significant problem..In this paper an evolutionary algorithm is proposed that uses approaches to solution construction and modification utilized by practitioners in the field. T