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Titlebook: Isoenzymes; C. C. Rider,C. B. Taylor Book 1980 C. C. Rider, C. B. Taylor 1980 cancer.development.diagnosis.enzyme.evolution.genetics.regul

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Isoenzymes in metabolic regulation,the evolution of the special control systems which are required for individual tissues or cells to carry out their separate metabolic roles. The purpose of this chapter is, therefore, to examine the ways in which variations in isoenzyme properties can allow an enzyme to serve different functions in
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Introduction, heterogeneity has accrued and it now seems likely that at least half of all enzymes exist as isoenzymes. This is important in many areas of biological and medical science. Thus isoenzyme studies have provided the main experimental substance for the neutral drift controversy in genetics and evolutio
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Isoenzymes in genetics and evolution,esult of a different gene, whether we are considering an enzyme encoded by multiple alleles at a single locus, or multiple loci. Therefore, wherever the isoenzyme subunit type is found, the gene coding for it is not only present, but is being expressed. In this way the isoenzyme subunit is a marker
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Isoenzymes in development and differentiation,adult organism from a single fertilized cell. A major aspect of this process is tissue differentiation, i.e. the generation of the many cell types, each with specific physical and metabolic character­istics, which are essential to the diverse and integrated functions of that adult organism. It will
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Isoenzymes in diagnosis and disease,ermeable to enzymes and hence enzyme activities in the serum are very low compared with those in cells. Tissue damage which renders the cell membrane permeable will result in the leakage of soluble cell contents, including enzymes, into the serum. In diseases where this takes place the serum concent
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