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Titlebook: Isoenzymes; D. W. Moss Book 1982 Chapman and Hall Ltd 1982 activation.biological.enzyme.enzymology.evolution.gene.genes.hydrogen.peptide.p

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发表于 2025-3-21 17:39:32 | 显示全部楼层 |阅读模式
书目名称Isoenzymes
编辑D. W. Moss
视频video
图书封面Titlebook: Isoenzymes;  D. W. Moss Book 1982 Chapman and Hall Ltd 1982 activation.biological.enzyme.enzymology.evolution.gene.genes.hydrogen.peptide.p
描述The increased interest in multiple forms of enzymes that began with the application of new methods of fractionation to preparations of enzymes and other proteins some 25 years ago led quickly to an appreciation that the existence of enzymes in multiple forms, or isoenzymes, is a general phenomenon. The results of pioneering studies and those which followed in the early years of isoenzyme research consisted, not surprisingly, mainly of descriptions of the existence and characteristics of hetero­ geneity in various enzyme systems. Summaries of these results were provided in books such as J . H. Wilkinson‘s I soenzymes, the first edition of which appeared in 1965. Some clearer ideas of the nature of the phenomena had become apparent by the time that the second edition of Isoenzymes was called for in 1970, and a limited use of the word isoenzymes itself, to describe only certain of the various categories of enzyme multiplicity then recognized, was already being proposed. Nevertheless, a largely enzyme-by-enzyme oTganization of the contents of the book was still appropriate. Considerable advances, both experimental and conceptual, were made in isoenzyme research in the 1970s, and in 197
出版日期Book 1982
关键词activation; biological; enzyme; enzymology; evolution; gene; genes; hydrogen; peptide; phylogeny; plants; prote
版次1
doihttps://doi.org/10.1007/978-94-009-5886-9
isbn_softcover978-94-009-5888-3
isbn_ebook978-94-009-5886-9
copyrightChapman and Hall Ltd 1982
The information of publication is updating

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Differences in Properties between Multiple Forms of Enzymes,ow its specific secondary and tertiary structures, imply that most modifications of the amino acid sequence of the one or more chains which constitute a given protein will result in some observable change in its properties. The extent of such changes is potentially very wide, depending on the nature
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Distribution and Biological Functions of Multiple Forms of Enzymes,ans of adapting patterns of metabolism to the evolving needs of the organism in which they occur. It is to be expected, therefore, that the distribution of isoenzymes will not be uniform throughout the organism and wide variations in the activity of different isoenzymes do indeed occur, between orga
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Multiple Forms of Enzymes in Ontogeny, tissues in the course of normal development, or in response to environmental change Pathological changes, also, may be associated with alterations in the activities of specific isoenzymes. Both physiological and pathological alterations in isoenzyme patterns are important, not only for the insights
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Multiple Forms of Enzymes in Diagnostic Enzymology,ymes of the blood clotting system, being secreted into the extracellular fluids. Although small samples of almost any organ can now safely be obtained by biopsy techniques, chemical analysis of these samples, including the measurement of enzyme activities, has so far found little diagnostic applicat
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Multiple Forms of Enzymes and the Emergence of the Isoenzyme Concept,and has remained, the most useful and practicable system. For equally valid reasons, the main effort in the systematic study of enzymes became concentrated on factors which influence the rate of the catalysed reaction, since this approach offered the best prospect of understanding the nature of the
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