| 书目名称 | Iron in Central Nervous System Disorders |
| 编辑 | Peter Riederer,M. B. H. Youdim |
| 视频video | |
| 丛书名称 | Key Topics in Brain Research |
| 图书封面 |  |
| 描述 | The role of the metals copper, zinc, magnesium, lead, manganese, mercury, lithium and aluminium in neuropsychiatric disease are well known and has been discussed on several occasions. Yet little attention has been paid to iron, the most abundant transitional metal in the body and the earth‘s crust. Iron plays a major role as a cofactor of numerous metabolic enzymes, it is important for DNA and protein synthesis, and has a crucial role in the oxygen carrying capacity of haemoglobin. Some of the most devastating diseases of systemic organs are associated with abnormal iron metabolism. Yet only very recently its role in the central nervous system has been considered. Thus nutritional iron defi ciency and iron overload afflict some 500-600 million people. It is also well recognized that too little or too much iron can produce profound effects on the metabolic state of the cell, and therefore the regulation of iron uptake and disposition is tightly relegated by the cell. Its transport into the cell and storage are handled by transferrin, ferritin and haemo siderin. Nowhere are these processes so well recognized as in the case of brain iron metabolism. Iron does not have ready access t |
| 出版日期 | Conference proceedings 1993 |
| 关键词 | Central Nervous System; DNA; Lipid; Nervous System; Oxidation; Parkinson; dopamine |
| 版次 | 1 |
| doi | https://doi.org/10.1007/978-3-7091-9322-8 |
| isbn_softcover | 978-3-211-82520-4 |
| isbn_ebook | 978-3-7091-9322-8Series ISSN 0934-1420 |
| issn_series | 0934-1420 |
| copyright | Springer-Verlag/Wien 1993 |
发表于 2025-3-21 17:42:22
