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Titlebook: Iron Deficiency and Overload; From Basic Biology t Shlomo Yehuda,David I. Mostofsky Book 2010 Humana Press 2010 Absorption.Iron absorption.

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Regulation of Iron Absorption and Distributionls of the proximal gastrointestinal tract is a highly regulated physiological process that maintains body iron homeostasis..• Iron efflux from cells occurs through the transporter ferroportin..• Hepcidin is a plasma peptide that regulates plasma iron levels by controlling the iron export function of
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Iron as Nutrient: Strategies for Iron Acquisition and Usage by Pathogenic Microorganismsderophores and the molecular mechanisms required to synthesize, secrete, and ultimately import them are known virulence factors in many pathogenic bacteria..• Extraintestinal pathogenic . as well as . possess a five-gene apparatus to modify siderophores in order to overcome the host’s innate immune
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Iron Deficiency and Excess in the Brain: Implications for Cognitive Impairment and Neurodegenerationon by roughly 35% as contrast to a 90% depletion in the liver. Thus it is tightly controlled. It is associated with impairment of cognition and learning processes which may result from alteration in dopaminergic, at the level of its receptor subsensitivity, and increased opiate neurotransmission. Ot
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Stress, Immunology, and Cytokinesferent way..• There is a close connection between stress, cytokines, and the function of T helper..• Glucocortecoids and catecholamines, the major stress hormones, inhibit IL-12 and increase IL-10, thus causing a switch from Th1 to Th2..• Glucocortecoids and catecholamines induced by stress inhibit
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