书目名称 | Ion Channels and Ion Pumps |
副标题 | Metabolic and Endocr |
编辑 | Piero P. Foà (Professor Emeritus),Mary F. Walsh (A |
视频video | http://file.papertrans.cn/476/475152/475152.mp4 |
丛书名称 | Endocrinology and Metabolism |
图书封面 |  |
描述 | Omnis cellula e cellula, "every cell from a cell," was dogma to the 19th century cellular physiologist and the cornerstone of Virchow‘s Cellular pathologie. "Spread out a cell into a layer and you will find that, in ceasing to be a cell, it has ceased to act as such," wrote the British 1 physiologist G . R. Lewes more than a century age. "The cell remains vital as long as its wall remains intact . . . " keeping its content "pure and clear" and thus preserving the "vital principle" within, echoed Claude 2 Bernard a few years later. The notion of the cell membrane as a pro tecting envelope held sway until it became clear that it could not account for the "coalescence" of poorly differentiated embryonic "vesicles" and for their transformation into "cell-like structures" capable of auto regulation and yet subject to what the grandfather of one of us defined as the "federal obligations imposed by the whole organism. ,,3 A new concept was needed, and soon the membrane was described as a structure capable of uniting as well as separating adjacent cells. Morphologic evidence for this dual function was obtained several years later when the electron microscope revealed the existence of t |
出版日期 | Book 1994 |
关键词 | ATP; Calcium; Diabetes; G proteins; Immunity; Nucleotide; cellular mechanisms; homeostasis; insulin; insulin |
版次 | 1 |
doi | https://doi.org/10.1007/978-1-4612-2596-6 |
isbn_softcover | 978-1-4612-7599-2 |
isbn_ebook | 978-1-4612-2596-6Series ISSN 0938-040X |
issn_series | 0938-040X |
copyright | Springer-Verlag New York, Inc. 1994 |