Titlebook: Iodine and the Brain; G. Robert DeLong,Jacob Robbins,Peter G. Condliffe Book 1989 Plenum Press, New York 1989 biology.brain.cortex.metabol

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The Fetus and Iodine Deficiency: Marmoset and Sheep Models of Iodine Deficiencyticularly important during the period of fetal development. The available epidemiological evidence has been complemented by experimental studies of fetal development in animal models. These have focussed particularly on fetal brain development because of its obvious importance. Definite effects have

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Placental Deiodination of the Thyroid Hormones these hormones and their action at the cellular level. For example, the rate of 5. or outer ring PIU sensitive type I deiodination of T4 is a major factor in the regulation of the plasma triiodothyronine (T.) concentration in the euthyroid state and PIU insensitive Type II 5’-deiodination of T. pla

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Thyroid Hormone Transport from Blood into Brain Cellsroversy, include the interaction of the hormones with “minor” transport protein in plasma, the kinetics of transcapillary movement, the presence of specific receptors for the carrier proteins and the hormones on endothelial and epithelial cell membranes, and specific transport mechanisms within cell organelles.

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Thyroid Hormone Receptors in the Developing Brain regulation of the properties of the receptor, its affinity for the chromatin and its affinity for the hormones through phosphorylation, ribosylation, acetylation induced a.o. by thyroid hormones [7–9].

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Thyroid Influences on the Developing Cerebellum and Hippocampus of the Ratal development during the neonatal and early postnatal period in the rat, which is roughly equivalent to the first year of life in the human (Salmon, 1936; Scow and Simpson, 1945; Eayrs and Taylor, 1951; Eayrs and Horn, 1955; Hamburg and Vicari, 1957; Eayrs, 1961).

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