书目名称 | Investigations of Cellular and Molecular Biophysical Properties by Atomic Force Microscopy Nanorobot |
编辑 | Mi Li |
视频video | |
概述 | Awarded as an Outstanding PhD thesis by the Chinese Academy of Sciences in 2015.Describes a comprehensive study on using atomic force microscopy (AFM) to investigate single-cell and single-molecule ac |
丛书名称 | Springer Theses |
图书封面 |  |
描述 | .This book presents methodological and application research in detecting cellular and molecular biophysical properties based on atomic force microscopy (AFM) nanorobotics. Series methods for in situ label-free visualizing and quantifying the multiple physical properties of single cells and single molecules were developed, including immobilization strategies for observing fine structures of living cells, measurements of single-cell mechanics, force recognition of molecular interactions, and mapping protein organizations on cell surface. The biomedical applications of these methods in clinical lymphoma treatments were explored in detail, including primary sample preparation, cancer cell recognition, AFM detection and data analysis. Future directions about the biomedical applications of AFM are also given.. |
出版日期 | Book 2018 |
关键词 | Atomic Force Microscopy; AFM; Lymphoma targeted therapy; Cell mechanics; Single-molecule force spectrosc |
版次 | 1 |
doi | https://doi.org/10.1007/978-981-10-6829-4 |
isbn_softcover | 978-981-13-4954-6 |
isbn_ebook | 978-981-10-6829-4Series ISSN 2190-5053 Series E-ISSN 2190-5061 |
issn_series | 2190-5053 |
copyright | Springer Nature Singapore Pte Ltd. 2018 |