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Titlebook: Introduction to Biopsy Interpretation and Surgical Pathology; James Cressee Elphinstone Underwood Book 1987Latest edition Springer-Verlag

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Immunohistology, range of otherwise invisible substances in cells and tissue sections. Although immunofluorescence has been available since the 1940s (Coons et al. 1941), this technique has been difficult to employ routinely in clinical histopathology because of the almost universal requirement for frozen sections
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Interpretation of Histological Appearances,diagnosing the identity of a friend met in the street, a brand of food on the supermarket shelf, or a histological section of a colorectal adenocarcinoma; the diagnostic process is the same in each instance; what distinguishes each example is the previous experience of the observer that enables diag
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Borderline Lesions, Pseudomalignancy and Mimicry,nce of this point is emphasised in this chapter. A distinction will first be drawn between the concept of borderline lesions, where two or more named conditions (diagnoses) occur within the same continuous disease category, and genuine mimicry, where two or more entirely separate diseases share morp
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Rapid Frozen Section Diagnosis,sthesia and aseptic techniques enabled surgeons to perform longer and more ambitious operations. Second, improvements in the optics of microscopes due to innovations such as the Abbe condenser and achromatic lenses made it possible for histologists to decipher the images of relatively inferior secti
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Quantitative Methods,on is necessary to reduce observer bias and to permit the application of Statistical methods for the analysis of results. There is, however, an increasing interest in the application of quantitative methods to the Solution of diagnostic problems in clinical biopsies (Baak et al. 1982).
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