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Titlebook: Introduction to Basics of Pharmacology and Toxicology; Volume 3 : Experimen Mageshwaran Lakshmanan,Deepak Gopal Shewade,Gerard Book 2022 Sp

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书目名称Introduction to Basics of Pharmacology and Toxicology
副标题Volume 3 : Experimen
编辑Mageshwaran Lakshmanan,Deepak Gopal Shewade,Gerard
视频video
概述Elaborates on the general principles of experimental pharmacology.Describes about the screening methods for the evaluation of different categories of drugs.Summarizes the various aspects of research m
图书封面Titlebook: Introduction to Basics of Pharmacology and Toxicology; Volume 3 : Experimen Mageshwaran Lakshmanan,Deepak Gopal Shewade,Gerard Book 2022 Sp
描述.This volume is designed to impart the fundamental concepts in experimental pharmacology, research methodology and biostatistics. Through this book, the readers will learn about different methods involved in drug discovery, experimental animals and their care, equipments and the various bioassays used in experimental pharmacology. This book contains special sections on various drug screening methods involved in the evaluation of different body systems. Certain sections provide the healthcare professionals with the knowledge necessary to interpret clinical research articles, design clinical studies, and learn essential concepts in biostatistics in an expedient and concise manner. Basic principles and applications of simple analytical methods employed in drug analysis are well written under one section. ..It focuses on the basic and advanced laboratory techniques and also on computer simulated data, written extensively under the Biostatistics section. The methods used for drug analysis have been described in adequate detail with cross-references for further studies and comprehension. Overall, the book is designed systematically with four broad sections with extensive subdivisions for
出版日期Book 2022
关键词Experimental Pharmacology; Drug Screening; Research Methodolgy; Biostatistics; Instrumentation in Drug A
版次1
doihttps://doi.org/10.1007/978-981-19-5343-9
isbn_softcover978-981-19-5345-3
isbn_ebook978-981-19-5343-9
copyrightSpringer Nature Singapore Pte Ltd. 2022
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Care and Handling of Laboratory Animalster, gerbils, ferret, dog, and cat should be maintained in a hygienic environment provided with good ventilation, day/night cycle, and humidity condition. The living environment of the experimental animals should be maintained uniformly throughout their lifespan to minimize stress and anxiety. Handl
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Biological Sample Collection from Experimental Animalsllection of biological samples should be the least stressful and painful. Prior permission should be obtained from the animal ethics committee for collection of biological samples from the animals. In the laboratory, rats, mice, guinea pigs and rabbits are most commonly used for pharmacological expe
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Bioassay and Experiments on Isolated Muscle Preparationsogical effect. It can be done in-vitro, in-vivo, or ex-vivo technique. Bioassay is commonly used to measure or isolate active principles whose chemical composition is unknown. Various methods like direct endpoint, matching, bracketing, and multiple point assays are available for assaying agonists. F
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Experiments on Anaesthetized Intact Animalse most commonly used animals for intact whole animal experiments today. Measurement of blood pressure and spleen volume are commonly performed on dogs, while the nictitating membrane model of cat is a classical example for whole animal experiments. Spinal cat is another classical model used to study
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Principles of EC50, ED50, pD2 and pA2 Values of Drugskes into account the relationship between a particular dose of a drug and the corresponding effect produced by it. The commonly used “dose descriptors” include EC. (half maximal effective concentration), LC. (median lethal concentration), ED. (median effective dose), TD. (median toxic dose), LD. (me
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