| 书目名称 | Intrinsically Disordered Proteins |
| 编辑 | Vladimir N. Uversky |
| 视频video | |
| 概述 | Discusses applications of IDPs and IDPRs as potential drug targets.Includes an introduction to the concept of protein intrinsic disorder.Provides an overview of current literature in the field.Include |
| 丛书名称 | SpringerBriefs in Molecular Science |
| 图书封面 |  |
| 描述 | In this brief, Vladimir Uversky discusses the paradigm-shifting phenomenon of intrinsically disordered proteins (IDPs) and hybrid proteins containing ordered domains and functional IDP regions (IDPRs). Beginning with an introduction to the concept of protein intrinsic disorder, Uversky then goes on to describe the peculiar amino acid sequences of IDPs, their structural heterogeneity, typical functions and disorder-based binding modes. In the final sections, Uversky discusses IDPs in human diseases and as potential drug targets. This volume provides a snapshot to researchers entering the field as well as providing a current overview for more experienced scientists in related areas. |
| 出版日期 | Book 2014 |
| 关键词 | Binding Promiscuity; Conformational Ensemble; Intrinsically Disordered Protein; Protein Folding; Protein |
| 版次 | 1 |
| doi | https://doi.org/10.1007/978-3-319-08921-8 |
| isbn_softcover | 978-3-319-08920-1 |
| isbn_ebook | 978-3-319-08921-8Series ISSN 2191-5407 Series E-ISSN 2191-5415 |
| issn_series | 2191-5407 |
| copyright | The Author(s) 2014 |
发表于 2025-3-21 18:01:58
