Titlebook: Intraovarian Control Mechanisms; Cornelia P. Channing,Sheldon J. Segal Book 1982 The Editor(s) (if applicable) and The Author(s), under ex

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Characterization of LH/hCG Receptor Binding Inhibitor in Corpora Lutea of Human and Sheep Ovaries,rat ovaries. It was partially purified and found to be a peptide of approximately 3800 daltons. Sakai et al. (1977) found a similar inhibitor in corpora lutea of porcine ovaries, but not in other ovarian tissues. These crude porcine luteal extracts inhibited basal and LH-stimulated progesterone secr

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Stimulation of Granulosa Cell Maturation by Follicular Fluid,sed steroidogenic activity (Channing, 1970), increased cellular content of steroidogenic organelles (Rigby et al., 1980a), enhanced responsiveness to the gonadotrophins, and enhanced adenyl cyclase activity (Channing and Ledwitz-Rigby, 1974). Concomitant with follicular enlargement granulosa cell de

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Oocyte Maturation Inhibitor: A 1981 Perspective,n of meiosis includes breakdown of the germinal vesicle (GVB), expulsion of the first polar body and progress to the metaphase of the second meiotic division, I will refer to the first change, namely GVB as “resumption of meiosis” or “maturation” or in short “oocyte maturation.”

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Meiotic Arresting Substance Separated from Porcine Ovarian Granulosa Cells and Hypothetical Arresti surge of luteinizing hormone (LH) at each ovarian cycle (Shuetz, 1969; Tsafriri, 1978a), although the ability to complete the first meiotic division is related as well to the stage of follicular development (Tsafriri and Channing, 1975a; Sorensen and Wassarman, 1976).

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Purification, Characterization, and In Vitro Production of Inhibin,ntrations seem to be inversely correlated with the number of developing large follicles (see Welschen et al., 1980). Finally, a specific suppression of FSH was observed after intrasplenic transplantation of ovaries into castrated male or female rats (Uilenbroek et al., 1978).