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Titlebook: Intraductal Papillary Mucinous Neoplasm of the Pancreas; Masao Tanaka Book 2014 Springer Japan 2014 branch duct type.dysplasia.main duct t

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Histological Subclassification and Its Clinical Significancehe prognosis is less favorable, around 90 % and 70 % in the 5- and 10-year survivals. The pancreatobiliary-type IPMNs show complex fernlike papillae consisted of high-grade dysplastic cells expressing MUC1 and MUC5AC. They are often associated with tubular adenocarcinoma and, hence, the prognosis is
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Endosonographyecise diameter as an indicator of the malignant potential of BD- or mixed-type IPMN. EUS can depict MNs as slightly hyperechoic papillary projections. The differentiation between MNs and mucin plugs can be challenging, and contrast-enhanced EUS imaging may be needed to demonstrate enhancement of the
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Diagnostic Investigation Using Pancreatic Juicejuice cytology also provides the information regarding subtypes of IPMNs, namely, gastric, intestinal, pancreatobiliary, and oncocytic by the assessments of morphological features and immunohistochemistry. On the other hand, it remains unclear which patients with IPMN are indication for pancreatic j
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Development of Pancreatic Carcinoma in IPMN Patientsign gastric-type IPMN in the absence of . mutations, and so . mutations might be useful in this context. Both of concomitant PDAC and invasive IPMN may be characterized by more favorable biological behaviors or be diagnosed earlier than ordinary PDAC. Worsening diabetes and elevation of CA 19-9 have
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Surveillance of Branch-Duct IPMN: Methods and Frequencyile the evidence to support current recommendations is limited, the trend of available data continues to support deliberate observation for most BD-IPMNs without high-risk stigmata or worrisome features of malignancy. Newer diagnostic tools with better accuracy for diagnosing BD-IPMNs and their dysp
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Method of Resection of Branch-Duct IPMN benign BD-IPMN is good. However, the risk of progressive or new IPMN disease, including invasive cancer, in patients undergoing resection of BD-IPMN is significant, and these individuals need to be followed closely and indefinitely.
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Timing of Resection of Branch Duct IPMN and tumor location. The complexity of making decisions in regard to patients with BD-IPMN has precluded the development of standard treatment guidelines applicable to every patient. Rather, treatment must be tailored to the clinical situations of individual patients.
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