| 书目名称 | Intracellular Messengers | | 编辑 | Alan A. Boulton,Glen B. Baker,Colin W. Taylor | | 视频video | | | 丛书名称 | Neuromethods | | 图书封面 |  | | 描述 | Despite the success of earlier Neuromethads volumes, I was initially reluctant to edit a further volume because my own - search is concerned with nonneural tissues. I changed my mind for two simple reasons. First, though the sheer diversity of ext- cellular signal molecules is staggering, still more impressive is the remarkably small number of transmembrane signaling processes they recruit- their receptors either have integral ion channels or enzyme activities, or else they catalytically activate G proteins. Likewise, when we look to the final intracellular t- gets of these signaling pathways, they are stucturally diverse, but again there are common themes: the response may either be the gating of an ion channel, or else the phosphorylation of a target protein. Such conservation of signaling mechanisms is both impressive and convenient, and provides my justification for asking authors with interests in diverse tissues to contribute their methodological expertise to this volume. Second, I think it would be difficult to overestimate the extent to which our understanding of intracellular signaling has been transformed by new and improved methodology. Thus, simple methods for measuring | | 出版日期 | Book 1992 | | 版次 | 1 | | doi | https://doi.org/10.1385/0896032078 | | isbn_softcover | 978-1-4899-4027-8 | | isbn_ebook | 978-1-59259-625-6Series ISSN 0893-2336 Series E-ISSN 1940-6045 | | issn_series | 0893-2336 | | copyright | Springer Science+Business Media New York 1992 |
The information of publication is updating
|
|
发表于 2025-3-21 19:19:01
