| 书目名称 | Intracellular Delivery III |
| 副标题 | Market Entry Barrier |
| 编辑 | Aleš Prokop,Volkmar Weissig |
| 视频video | |
| 概述 | Comprehensive set of reviews dealing with cellular (tissue) and intracellular targeting of nanovehicles.Covers classical and computational means of nanovehicle targeting.Delivers important application |
| 丛书名称 | Fundamental Biomedical Technologies |
| 图书封面 |  |
| 描述 | A critical review is attempted to assess the status of nanomedicine entry onto the market. The emergence of new potential therapeutic entities such as DNA and RNA fragments requires that these new “drugs” will need to be delivered in a cell-and organelle-specific manner. Although efforts have been made over the last 50 years or so to develop such delivery technology, no effective and above all clinically approved protocol for cell-specific drug delivery in humans exists as yet. Various particles, macromolecules, liposomes and most recently “nanomaterials” have been said to “show promise” but none of these promises have so far been “reduced” to human clinical practice. .The focus of this volume is on cancer indication since the majority of published research relates to this application; within that, we focus on solid tumors (solid malignancies). Our aim is critically to evaluate whether nanomaterials, both non-targeted and targeted to specific cells, could be of therapeutic benefit in clinical practice. The emphasis of this volume will be on pharmacokinetics (PK) and pharmacodynamics (PD) in animal and human studies. .Apart from the case of exquisitely specific antibody-based drugs, |
| 出版日期 | Book 2016 |
| 关键词 | Biochemical targeting; Cellular (tissue) targeting; Computational means of target discovery; Discovery |
| 版次 | 1 |
| doi | https://doi.org/10.1007/978-3-319-43525-1 |
| isbn_softcover | 978-3-319-82846-6 |
| isbn_ebook | 978-3-319-43525-1Series ISSN 1559-7083 Series E-ISSN 2626-8655 |
| issn_series | 1559-7083 |
| copyright | Springer International Publishing Switzerland 2016 |
发表于 2025-3-21 17:05:40
