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Titlebook: International Symposium: Retroviruses and Human Pathology; Robert C. Gallo,Dominique Stehelin,Oliviero E. Var Book 1985 The Humana Press I

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书目名称International Symposium: Retroviruses and Human Pathology
编辑Robert C. Gallo,Dominique Stehelin,Oliviero E. Var
视频video
丛书名称Experimental Biology and Medicine
图书封面Titlebook: International Symposium: Retroviruses and Human Pathology;  Robert C. Gallo,Dominique Stehelin,Oliviero E. Var Book 1985 The Humana Press I
描述For decades retroviruses have been riding the crest of a wave of experimental research directed toward the identification of an infectious agent of human neoplastic diseases. In the early 1970s, several scientists successfully demonstrated the presence of retroviruses in numerous animal species and proved their etiological role in some related diseases. Corresponding findings in humans were somewhat discouraging. Although financial support for this line· of research declined, a few dedicated retrovirologists survived and continued to collect more biological information and technological expertise that opened a new approach to the search for a human retrovirus. The rewards came with the discovery that the genes responsible for neoplastic transformation (oncogenes) are of cellular origin and can be shuttled about by retroviruses, and with the identification of a new family of Human T-cell Lymphotrophic retroViruses (HTLV) from patients with diseases ranging from leukemia to the acquired immunodeficiency syndrome (AIDS). An understanding of the role and significance of retroviruses in human pathology requires basic knowledge of the major animal systems studied. With this perspective i
出版日期Book 1985
关键词AIDS; Antigen; diseases; histocompatibility; immunodeficiency; infection; infections; leukemia; molecular bi
版次1
doihttps://doi.org/10.1007/978-1-4612-5008-1
isbn_softcover978-1-4612-9396-5
isbn_ebook978-1-4612-5008-1
copyrightThe Humana Press Inc. 1985
The information of publication is updating

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The Biology of Endogenous Leukemia Viruses: A Study of the DBA/2 Mouses is commonly accepted. To evaluate the role of the endogenous viruses in a system which has not been preselected for a specific oncogenic response, we have studied the C-type retroviruses of the low-leukemia mouse strain DBA/2.
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Book 1985man neoplastic diseases. In the early 1970s, several scientists successfully demonstrated the presence of retroviruses in numerous animal species and proved their etiological role in some related diseases. Corresponding findings in humans were somewhat discouraging. Although financial support for th
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The Envelope Gene of Mammalian Retroviruses: Analysis of its Structure Reveals Specific Recombinatio gene product. Recombination of the viral DNA with cellular sequences is a prerequisite for viral replication (1) and induction of disease (13). Analysis of the viral sequences at the points of recombination has revealed a eucaryotic consensus sequence for recombination.
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