书目名称 | International Symposium: Retroviruses and Human Pathology |
编辑 | Robert C. Gallo,Dominique Stehelin,Oliviero E. Var |
视频video | |
丛书名称 | Experimental Biology and Medicine |
图书封面 |  |
描述 | For decades retroviruses have been riding the crest of a wave of experimental research directed toward the identification of an infectious agent of human neoplastic diseases. In the early 1970s, several scientists successfully demonstrated the presence of retroviruses in numerous animal species and proved their etiological role in some related diseases. Corresponding findings in humans were somewhat discouraging. Although financial support for this line· of research declined, a few dedicated retrovirologists survived and continued to collect more biological information and technological expertise that opened a new approach to the search for a human retrovirus. The rewards came with the discovery that the genes responsible for neoplastic transformation (oncogenes) are of cellular origin and can be shuttled about by retroviruses, and with the identification of a new family of Human T-cell Lymphotrophic retroViruses (HTLV) from patients with diseases ranging from leukemia to the acquired immunodeficiency syndrome (AIDS). An understanding of the role and significance of retroviruses in human pathology requires basic knowledge of the major animal systems studied. With this perspective i |
出版日期 | Book 1985 |
关键词 | AIDS; Antigen; diseases; histocompatibility; immunodeficiency; infection; infections; leukemia; molecular bi |
版次 | 1 |
doi | https://doi.org/10.1007/978-1-4612-5008-1 |
isbn_softcover | 978-1-4612-9396-5 |
isbn_ebook | 978-1-4612-5008-1 |
copyright | The Humana Press Inc. 1985 |