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Titlebook: International Conference on Emerging Trends in Engineering (ICETE); Emerging Trends in S Suresh Chandra Satapathy,K. Srujan Raju,George A.

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K. Surya Prakash,Kone Srimannarayana,Pradeep Kumar Kaatnam,Abhinav Dayalhave been correlated with therapeutic effects. It is thus important to understand the influence of various factors such as age, disease states, and concurrent therapy on the drug’s kinetics, as these factors often alter drug pharmacokinetics (and therefore therapeutic efficacy) and are present in a
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D. Babu Rao,D. Nageswara Raoated to disease from those due to aging.. This is particularly important in deciding whether, for a suspected clinical syndrome, the clinician should start therapy with corticosteroids, a group of drugs that if not given cautiously, even in younger patients, may result in significant side effects. F
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Paul Awoyera,Ravindran Gobinath,Sandela Haripriya,Poongodi Kulandaisamiounds. However, identification of drug targets by experiments is usually expensive and time-consuming. Therefore, various types of computational methods have been developed for prediction of drug targets over the past decade, such as molecular docking-based, pharmacophore-based, similarity-based, ma
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Paul Awoyera,Ravindran Gobinath,Chinyere Nwankwo,Palanisamy Murthi,Annabathina Sivakrishnacovered by phenotypic-based screening methods. However, identifying molecular targets for these bioactive compounds is a very laborious process. With the development and advancements in new methodologies and techniques for identification and biological analysis, various target identification methods
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Balendra Mouli Marrapu,Ravi Sankar Jakkaride channel protein important in cystic fibrosis) or overproduction of a normal protein (such as the products of certain oncogenes). We can achieve this goal by replacing the defective gene or by reducing the overexpression of the target gene using an antisense strategy, thus reducing the productio
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Chaitanya Lakeshri,Kaustubh Salvigulations and proliferate incessantly. Furthermore, the accumulation of these mutations confers metastatic abilities to the tumor cells, which help them in contriving various features essential for invasion of the host tissues and evading immune surveillance and thus spreading to distant sites. Meta
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