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Titlebook: International Conference on Advancements of Medicine and Health Care through Technology; 5th – 7th J; MEDITECH 2014 Simona Vlad,Radu V. Ciu

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I. Bărbănţan,R. Potoleas differences, in vitro/in vivo differences, age-related differences, and normal/disease differences, and these need to be understood in order to guide rational drug discovery and development. To address this issue, we have developed an absolute quantification method of protein expression, called qu
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V. Ţărmure,O. C. Almăşan,D. Buhăţel,A. Ilea,P. Jiman,M. Iancu,A. Pops differences, in vitro/in vivo differences, age-related differences, and normal/disease differences, and these need to be understood in order to guide rational drug discovery and development. To address this issue, we have developed an absolute quantification method of protein expression, called qu
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Radu Răzvan Slăvescu,Alin-Cristian Groşan,Kinga Cristina Slăvescu expression levels of target proteins by quantitative targeted absolute proteomics (QTAP). Such proteomic techniques have been used in blood-brain barrier (BBB) research, and the output of these approaches has yielded substantial information. This chapter introduces two proteomic applications for un
发表于 2025-3-27 16:31:13 | 显示全部楼层
Radu Răzvan Slăvescu,Kinga Cristina Slăvescudelivery into the central nervous system (CNS). New strategies to circumvent the blood-brain barrier (BBB) have long been needed to utilize polar pharmaceuticals and large biotherapeutics for CNS disease treatment because the BBB is typically impermeable to such compounds. The increasing application
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M. Krenn,S. M. Danner,A. Schweiger,U. S. Hofstoetter,K. Minassian,W. Mayr in order to provide a basis for understanding drug delivery to the brain from a clinically relevant perspective. The most important concentrations to measure when determining drug distribution are those of the unbound drug, because it is the unbound drug that causes the pharmacological effect by in
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T. Surdea-Blaga,L. David,D. L. Dumitrascuivery in glioma therapy, which is the focus of this review, and much work has gone into the utilization of this technique. CED can be modeled using several equations that describe the transport of fluid into porous tissue. More practically, variability in CED catheters has been studied and catheters
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