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Titlebook: Interferon Alpha-2: Pre-Clinical and Clinical Evaluation; Proceedings of the S Daniel L. Kisner,J. F. Smyth Conference proceedings 1985 Mar

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Use in Hairy Cell Leukemia. An Update,rd of splenectomized patients subsequently develop increasing bone marrow involvement and signs of marrow underproduction. Since October, 1983, we have identified 16 patients with progressive HCL who have qualified for a trial of subcutaneous alpha-2 interferon. Of the 16 patients, the median age wa
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Clinical Trials in Non-Hematologic Malignancies,ducted in other sarcomas and carcinomas which may provide interesting leads regarding biological mechanisms of interferon activity as well as clinical areas for further study. Phase II studies with INTRON as well as other interferon products have been largely negative in most adult solid tumors, e.g
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cations of dissipativity theory in the stability of adaptive schemes in Chaps. .–.. Direct adaptation means that one has been able to rewrite the fixed parameter input ., in a form that is linear with respect to some unknown parameters, usually written as a vector ., i.e., ., where . is a known matr
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T. L. Nagabhushan,P. J. Leibowitzor linear and nonlinear dynamical systems. One of the key properties of a dissipative dynamical system is that the total energy stored in the system decreases with time. Dissipativeness can be considered as an extension of PR systems to the nonlinear case. Some relationships between positive real an
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D. Kisneri.e. with input equal to zero) have the important property that the amount of energy stored in the system remains unchanged or even decreases. This gives rise to the definition of Dissipative systems which is very useful in the synthesis of control systems. Different definitions are introduced to di
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