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Titlebook: Interface Oral Health Science 2009; Proceedings of the 3 Takashi Sasano (Dean and Professor),Osamu Suzuki ( Conference proceedings 2010 Spr

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Transient receptor potential channels and mechanobiologyPV1, TRPV2, TRPP1/TRPP2, TRPM4, TRPM7, and TRPA1 channels mediate mechanosensation. TRPC1, TRPC5, TRPC6, TRPV2, TRPV4, TRPM3, and TRPM7 channels are involved in osmosensation. I will review mechanosensitive channels and discuss their activation mechanism.
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Effect of Young’s modulus in metallic implants on atrophy and bone remodelingng treatment highly improves the strength of porous titanium and poly(methyl methacrylate) composite by keeping its Young’s modulus just equal to that of the cortical bone. TNTZ with low Young’s modulus inhibits the bone atrophy and enhances bone remodeling.
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Shear-stress-sensing and response mechanisms in vascular endothelial cellsd by flowing blood. This fact suggests that ECs recognize shear stress and transmit signals to the interior of the cell. Shear-stress-sensing and response mechanisms, however, have not been fully understood. We have demonstrated that ECs are capable of converting information regarding shear stress i
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Strategies underlying research in tooth regenerative therapy as a possible model for future organ reinjury, or aging. We have previously developed a three-dimensional culture system with the aim of reconstituting a bioengineered organ germ at an early developmental stage. The regeneration of a functional tooth unit is critical issue to achieving proper oral function, including mastication. Recentl
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