Titlebook: Interaction of Immune and Cancer Cells; Magdalena Klink,Izabela Szulc-Kielbik Book 2022Latest edition The Editor(s) (if applicable) and Th

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Cancer Immunoediting: Elimination, Equilibrium, and Immune Escape in Solid Tumors,ed by the current concept of . consisting of three phases: elimination, equilibrium, and escape. Solid tumors composed of both cancer and host stromal cells are an example how the three phases of cancer immunoediting functionally evolve and how tumor shaped by the host immune system gets finally res

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Adoptive T-cell Immunotherapy: Perfecting Self-Defenses,hese characteristics, their natural antitumor response may be insufficient. Numerous clinical trials in terminally ill cancer patients testing the design of novel and efficient immunotherapeutic approaches based on the adoptive transfer of autologous tumor-specific T lymphocytes have shown encouragi

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Monoclonal Antibodies to CTLA-4 with Focus on Ipilimumab,plays a critical role in suppressing autoimmunity and maintaining immune homeostasis. Because of its inhibitory activity on T cells, CTLA-4 has been investigated as a drug target to induce immunostimulation, blocking the interaction with its ligands. The antitumor effects mediated by CTLA-4 blockade