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Titlebook: Intensive Care Medicine; Annual Update 2002 Jean-Louis Vincent (Head) Book 2002 Springer Science+Business Media New York 2002 Trauma.anesth

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Molecular Mechanisms of Complement Activation during Ischemia and Reperfusionsease. The obvious treatment of ischemia is reperfusion of the jeopardized organ or tissue. However, when ischemia is too severe, reperfusion may exacerbate rather than limit tissue damage, a phenomenon known as ischemia/reperfusion (I/R)-injury. A number of studies have been performed to unravel th
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Gender and Cell-mediated Immunity Following Trauma, Shock, and Sepsis causes of death for young adults (<30 years of age) in the United States. Trauma represents a severe form of injury including bone fracture, penetrating soft tissue injury, (i.e., gunshot wounds), thermal injury and protracted surgical procedures. Many forms of traumatic injury, such as penetrating
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Regulatory Role of Alveolar Macrophages and Cytokines in Pulmonary Host Defense Infectious agents that have passed the structural defenses and have entered the terminal airways may cause pneumonia, one of the most common infectious diseases. Both the growing number of immunocompromised patients susceptible to pneumonia, and the widespread use of antibiotics that has led to a r
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Apoptosis in Pneumoniaeatures observed in necrosis [1]. The term apoptosis, from the Greek word meaning ‘falling off’, was adopted to describe this highly conserved genetic program leading to regulated cellular self-destruction. Subsequent investigations showed that this programmed cell death was crucial during fetal dev
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The Immunomodulatory Effects of Anesthetic and Analgesic Agentse intensive care unit (ICU) care by rendering tolerable interventions that would otherwise be akin to torture — mechanical ventilation, dressing changes, cardioversion, and invasive procedures such as line insertion or bronchoscopy, to name a few. These agents modulate the function of the central an
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