| 书目名称 | Integrins in Health and Disease |
| 副标题 | Key Effectors of Cel |
| 编辑 | Donald Gullberg,Johannes A. Eble |
| 视频video | |
| 概述 | Introduces the most important integrins and their biological functions.Discusses the role of integrins in tissue and tumor fibrosis.Explains the role of integrins as receptors for bacterial and viral |
| 丛书名称 | Biology of Extracellular Matrix |
| 图书封面 |  |
| 描述 | .Integrins are heterodimeric cell surface receptors which anchor cells to different extracellular matrix proteins or act as cell-cell receptors. They play pivotal roles not only across a wide range of physiological processes including tissue morphogenesis, wound healing, and regulation of cell growth, but also in numerous pathological conditions such as autoimmunity, infectious disease, and carcinogenesis...This book aims to provide readers a summary of the most important integrins and their respective biological functions. Readers will learn about knockout- and animal models to study the functionality of key collagen-, laminin-, and nephronectin-binding integrins. Additionally, the role of integrins in pathological tissue remodeling in joints and in developing and diseased cardiac tissue are discussed. Reviews of the current knowledge of the role of integrins in tissue and tumor fibrosis, angiogenesis and tumor progression are an important part of this work. Finally, the bookdiscusses integrins in the context of the immune system, how to target integrin-ligand interactions with antibodies, and the role of integrins as receptors for bacterial and viral cell invasion. ..Both experie |
| 出版日期 | Book 2023 |
| 关键词 | Integrins; Cell adhesion; Cell migration; Cell-extracellular matrix-signaling; Immunity; Intracellular in |
| 版次 | 1 |
| doi | https://doi.org/10.1007/978-3-031-23781-2 |
| isbn_softcover | 978-3-031-23783-6 |
| isbn_ebook | 978-3-031-23781-2Series ISSN 0887-3224 Series E-ISSN 2191-1959 |
| issn_series | 0887-3224 |
| copyright | The Editor(s) (if applicable) and The Author(s), under exclusive license to Springer Nature Switzerl |
发表于 2025-3-21 18:04:58
