| 书目名称 | Integrins and Ion Channels |
| 副标题 | Molecular Complexes |
| 编辑 | Andrea Becchetti,Annarosa Arcangeli |
| 视频video | |
| 概述 | Presents a series of essays on cellular models that have been studied.Gives a brief historical background, summarizes the elements of integrin structure and outlines the main biological problems that |
| 丛书名称 | Advances in Experimental Medicine and Biology |
| 图书封面 |  |
| 描述 | Interdisciplinarity is more often invoked than practised. This is hardly surprising, considering the daunting vastness of modern biology. To reach a satisfactory understanding of a complex biological system, a wide spectrum of conceptual and experimental tools must be applied at different levels, from the molecular to the cellular, tissue and organismic. We believe the multifaceted regulatory interplay between integrin receptors and ion channels offers a rich and challenging field for researchers seeking broad biological perspectives. By mediating cell adhesion to the extracellular matrix, integrins regulate many developmental processes in the widest sense (from cell choice between differentiation and proliferation, to tissue remodeling and organogenesis). Rapidly growing evidence shows that frequent communication takes place between cell adhesion receptors and channel proteins. This may occur through formation of multiprotein membrane complexes that regulate ion fluxes as well as a variety of intracellular signaling pathways. In othercases, cross talk is more indirect and mediated by cellular messengers such as G proteins. These interactions are reciprocal, in that ion channel sti |
| 出版日期 | Book 2010 |
| 关键词 | activation; antibody; biology; cancer; cell; development; ion channels; membrane; migration; proliferation; pr |
| 版次 | 1 |
| doi | https://doi.org/10.1007/978-1-4419-6066-5 |
| isbn_softcover | 978-1-4614-2583-0 |
| isbn_ebook | 978-1-4419-6066-5Series ISSN 0065-2598 Series E-ISSN 2214-8019 |
| issn_series | 0065-2598 |
| copyright | The Editor(s) (if applicable) and The Author(s), under exclusive license to Springer Science+Busines |
发表于 2025-3-21 19:06:01
