Titlebook: Integration and Excision of DNA Molecules; 28. Colloquium der G Peter Hans Hofschneider,Peter Starlinger Conference proceedings 1978 Spring

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Selectivity in the Integration of Viral DNA in Cells Infected and Transformed by Adenovirus,978), whereas the integrated form of adenovirus DNA cannot be detected when cellular DNA is completely inhibited. The mechanism by which viral and cellular sequences are linked is not at all understood. It is likely that cellular replication and recombination mechanisms play an important role in the insertion.

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Is Integration Essential for Mu Development?,The genome of bacteriophage Mu can integrate randomly in the chromosome of its host ., thereby causing mutations (Taylor, 1963). Random integration seems a more widespread phenomenon, since it was found that other DNA elements also show a more or less random integration: insertion sequences (IS) and transposons (Tn).

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Integrative Recombination of Bacteriophage Lambda: Genetics and Biochemistry,ombination has been, and continues to be, intensively studied from genetic, physiologic, and biochemical points of view. As a result there has been much progress in our understanding of the mechanism of this recombination, and this paper details several of these recent developments.

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The Role of IS-Elements in ,,oding capacity of some 3000–4000 average-sized polypeptide chains. The genes coding for these proteins are thought to be arranged in the chromosome in a sequence characteristic for a given bacterial species.

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,Adenovirus — Integration and Oncogenicity,y distinct virus group, exhibit a wide range of pathogenic responses in the many species from which they have been isolated or in which their oncogenic capabilities have been studied. Extensive reviews on adenoviruses have been published recently (Wold et al., 1977; Phil-ipson et al. 1976).

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