Titlebook: Insulin Resistance and Cancer; Epidemiology, Cellul I. George Fantus Book 2011 Springer Science+Business Media, LLC 2011 Hyperinsulinemia.I

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Insulin Resistance: Clinical Implications for Cancer Treatment and Prevention,the year 2030 [1]. As reviewed by Irwin et al. in another chapter [2], obesity has been linked to both cancer risk and cancer outcome. Although obesity, insulin resistance and hyperinsulinemia are interrelated [3], until recently the primary focus of epidemiologic and clinical cancer research has be

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Actions of Insulin As a Survival and Growth Factor: Akt, mTOR, and Regulation of Translation,vators of downstream pathways via the insulin receptor substrate (IRS) proteins. In a similar fashion, the insulin growth factor-1 receptor (IGF1R) transduces signals to downstream effectors via the PI3K and MAPK pathways.

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978-1-4614-2818-3Springer Science+Business Media, LLC 2011

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https://doi.org/10.1007/978-1-4419-9911-5Hyperinsulinemia; IGF Receptors; breast cancer; metabolic syndrome; obesity

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