书目名称 | Insights into Human Neurodegeneration: Lessons Learnt from Drosophila |
编辑 | Mousumi Mutsuddi,Ashim Mukherjee |
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概述 | This book provides recent advancements in the utilization of Drosophila melanogaster as a model organism in understanding the molecular basis of various neurodegenerative disorders.It also summarizes |
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描述 | .This book is aimed at generating an updated reservoir of scientific endeavors undertaken to unravel the complicated yet intriguing topic of neurodegeneration. Scientists from Europe, USA and India who are experts in the field of neurodegenerative diseases have contributed to this book. This book will help readers gain insight into the recent knowledge obtained from .Drosophila .model., .in understanding the molecular mechanisms underlying neurodegenerative disorders and also unravel novel scopes for therapeutic interventions.. .Different methodologies available to create humanized fly models that faithfully reflects the pathogenicities associated with particular disorders have been described here. It also includes information on the exciting area of neural stem cells. A brief discussion on neurofibrillary tangles, precedes the elaborate description of lessons learnt from .Drosophila .about Alzheimer‘s, Parkinson’s, Spinomuscular Atrophy, Huntington’s diseases, RNA expansion disorders and Hereditary Spastic Paraplegia. We have concluded the book with the use of .Drosophila. for identifying pharmacological therapies for neurodegenerative disorders. The wide range of topics covered h |
出版日期 | Book 2019 |
关键词 | Drosophila; Neurodegeneration; Molecular mechanisms; Genetic screen; Model system |
版次 | 1 |
doi | https://doi.org/10.1007/978-981-13-2218-1 |
isbn_softcover | 978-981-32-9913-9 |
isbn_ebook | 978-981-13-2218-1 |
copyright | Springer Nature Singapore Pte Ltd. 2019 |