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Titlebook: Insertional Mutagenesis Strategies in Cancer Genetics; Adam J. Dupuy,David A. Largaespada Book 2011 Springer Science+Business Media, LLC 2

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书目名称Insertional Mutagenesis Strategies in Cancer Genetics
编辑Adam J. Dupuy,David A. Largaespada
视频video
概述This work summarizes the contribution that insertional mutagenesis has made to our understanding of cancer.A variety of insertional mutagens are presented that have been used to study a variety of tum
图书封面Titlebook: Insertional Mutagenesis Strategies in Cancer Genetics;  Adam J. Dupuy,David A. Largaespada Book 2011 Springer Science+Business Media, LLC 2
描述The goal of this work is summarize the contribution that insertional mutagenesis has made to our understanding of cancer. A variety of insertional mutagens are presented that have been used to study a variety of tumor types in several model organisms. In addition, the impact of insertional mutagenesis in several gene therapy trials is discussed along with strategies to avoid such complications in future clinical trials.
出版日期Book 2011
关键词cancer; mouse models; mutagenesis; retroviral insertional mutagenesis; transposon insertional mutagenesi
版次1
doihttps://doi.org/10.1007/978-1-4419-7656-7
isbn_softcover978-1-4899-8134-9
isbn_ebook978-1-4419-7656-7
copyrightSpringer Science+Business Media, LLC 2011
The information of publication is updating

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Jesse D. Riordan,Laura M. Rogers,Katherine E. Berquam-Vrieze,Adam J. Dupuybe so broad that it can not be covered during the limited time of the conference. After discussion of several such topics, "Design and Synthesis of Organic Molecules Based on Molecular Recognition" was chosen. According to Albert Einstein we live in an era of perfect methods and confused aims. For e
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Lars U. Müller,Michael D. Milsom,David A. Williamsbe so broad that it can not be covered during the limited time of the conference. After discussion of several such topics, "Design and Synthesis of Organic Molecules Based on Molecular Recognition" was chosen. According to Albert Einstein we live in an era of perfect methods and confused aims. For e
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hould not be so broad that it can not be covered during the limited time of the conference. After discussion of several such topics, "Design and Synthesis of Organic Molecules Based on Molecular Recognition" was chosen. According to Albert Einstein we live in an era of perfect methods and confused a
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Retroviral Insertional Mutagenesis in Mouse Models of Leukemia and Lymphoma,and mortality, the study of these cancers has illuminated many important aspects of cancer development and biology. In fact, the leukemias and lymphomas are among the best-studied and well understood types of cancer from a genetic perspective. In part, this may derive from the fact that these types
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Gene Discovery by MMTV Mediated Insertional Mutagenesis,ling cascades mainly involved in cell proliferation, survival and development [46]. To develop novel specific therapeutic compounds for cancer treatment, identification of these cancer causing genes, and subsequently the oncogenic pathways in which these genes act, is of utmost importance. Although
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