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Titlebook: Insecticide Action; From Molecule to Org Toshio Narahashi,Janice E. Chambers Book 1989 Plenum Press, New York 1989 GABA.Glutamat.Mammalia.N

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书目名称Insecticide Action
副标题From Molecule to Org
编辑Toshio Narahashi,Janice E. Chambers
视频video
图书封面Titlebook: Insecticide Action; From Molecule to Org Toshio Narahashi,Janice E. Chambers Book 1989 Plenum Press, New York 1989 GABA.Glutamat.Mammalia.N
描述Intoxication of humans and animals has become increasingly important in recent years as has contamination of the environment by a variety of chemicals. In order to develop effective means by which such intoxication and contamination can be properly handled, it is imperative to know how these environmental agents act in humans and animals. Despite studies conducted by various investigators, the mechanisms of action of these environmental agents have not been fully elucidated. Insecticides are by no means an exception in terms of the seriousness of the problem and of the urgency of the need for such information. In order to complete a picture of the effects of any particular insecticide, it is of utmost importance that its actions at various levels ranging from those of molecules to whole animals be analyzed and synthesized. To understand the toxicological action on animals or humans, it is not sufficient to know the action at each level only. The actions at various levels must be integrated to construct a picture of the toxic effect on the intact organism. However, in spite of the large body of information that has been accumulated during the past few decades, little or no attempt h
出版日期Book 1989
关键词GABA; Glutamat; Mammalia; Nicotin; animals; insects; mutation; nervous system; pharmacology; phosphorus; prote
版次1
doihttps://doi.org/10.1007/978-1-4684-1324-3
isbn_softcover978-1-4684-1326-7
isbn_ebook978-1-4684-1324-3
copyrightPlenum Press, New York 1989
The information of publication is updating

书目名称Insecticide Action影响因子(影响力)




书目名称Insecticide Action影响因子(影响力)学科排名




书目名称Insecticide Action网络公开度




书目名称Insecticide Action网络公开度学科排名




书目名称Insecticide Action被引频次




书目名称Insecticide Action被引频次学科排名




书目名称Insecticide Action年度引用




书目名称Insecticide Action年度引用学科排名




书目名称Insecticide Action读者反馈




书目名称Insecticide Action读者反馈学科排名




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Insecticide Actions on Gaba Receptors and Voltage-Dependent Chloride Channels,y target for several other insecticides. The GABA. receptor has a high affinity (Kd in nM) for cyclodienes and binds them at the site that binds the convulsant t-butylbicyclophosphorothionate (TBPS). There is an excellent correlation between the toxicities of cyclodienes and their potencies in inhib
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Molecular Interactions of Organophosphates (OPs), Oximes and Carbamates at Nicotinic Receptors, electric organ, is the best characterized among agonist-gated ion channels (Karlin, 1980; Spivak and Albuquerque, 1982; Noda et al., 1983; Changeux et al., 1984; Sakmann et al., 1985). This molecule comprises the neurotransmitter recognition site and the ion channel and is formed by five polypeptid
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The Role of Ion Channels in Insecticide Action, the gating kinetics of the sodium channel including the prolongation of open time and the shift of activation voltage toward hyperpolarization are responsible for the hyperactivity of the nervous system. The different symptoms of poisoning in mammals caused by the two types of pyrethroids can be ac
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,Actions of Insecticides in Mammalian Central Nervous System — Use of in Vivo Hippocampal Evoked Potmpounds such as the convulsants pentylenetetrazol, picrotoxin, bicuculline, and the anticonvulsant agent diazepam were also examined for comparison purposes. The data demonstrates that picrotoxin, pentylenetetrazol, bicuculline, the cyclodiene insecticide dieldrin, and the hexachlorocyclohexane (ITC
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