Titlebook: Insect Nicotinic Acetylcholine Receptors; Steeve Hervé Thany Book 2010 The Editor(s) (if applicable) and The Author(s), under exclusive li

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Identification of Cholinergic Synaptic Transmission in the Insect Nervous System,r..The discovery of the snake toxin alpha-bungatoxin has helped to identify nicotinic acetylcholine receptors (nAChRs). In fact, nicotine when applied to insect neurons, resulted in the generation of an inward current through the activation of nicotinic receptors which were blocked by alpha-bungarot

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Diversity of Insect Nicotinic Acetylcholine Receptor Subunits,ne families are amongst the smallest known, receptor diversity can be considerably increased by the posttranscriptional processes alternative splicing and mRNA A-to-I editing which can potentially generate protein products which far outnumber the nAChR genes. These two processes can also generate sp

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Electrophysiological Studies and Pharmacological Properties of Insect Native Nicotinic Acetylcholinct, the alpha-bungarotoxin-sensitive nicotinic receptor subtypes described as homomeric could be also heteromeric receptors. Interestingly, some receptors mediating nicotinic responses have been termed ‘mixed’ receptors because they were blocked by a range of nicotinic and muscarinic antagonists..Fo

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Neonicotinoid Insecticides,s. Consequently, a number of derivatives and analogues of imidacloprid have been generated to date. In 1992, a new neonicotinoid using acetylcholine as the lead compound has been found. This was dinotefuran, which has a characteristic tetrahydro-3-furylmethyl group instead of the pyridine-like rings

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0065-2598 e precise in identifying the subunit composition of native insect nicotinic receptor subtypes, their functional properties and physiological roles.978-1-4939-5153-6978-1-4419-6445-8Series ISSN 0065-2598 Series E-ISSN 2214-8019

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Book 2010rom the identification of the first subunit sequences to be used as neonicotinoid insecticide target sites. Although a book of this nature can provide the details only of commonly published results, it is hoped that it may provide a useful guide to the newcomer to the field as well as to point out s