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Titlebook: Insect Aging; Strategies and Mecha Klaus-Günter Collatz,Rajindar S. Sohal Book 1986 Springer-Verlag Berlin Heidelberg 1986 Drosophila.aging

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l invention of nature, and death is her device to exhibit most life. The eminent British biologist Sir Vincent B. Wigglesworth noted in 1939 that insects are an ideal medium in which to study all problems of physiology. Many fundamental discoveries in biology, particularly genetics and development,
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Book 1986n of nature, and death is her device to exhibit most life. The eminent British biologist Sir Vincent B. Wigglesworth noted in 1939 that insects are an ideal medium in which to study all problems of physiology. Many fundamental discoveries in biology, particularly genetics and development, have been
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The Rate of Living Theory: A Contemporary Interpretation,to the earlier reports by Rubner (1908), who noted that the metabolic energy expended per gram body weight during lifetime in five mammalian species, which differed six fold in longevity, was similar, around 200kcal. He proposed that duration of life depended on the rate of expenditure of this limited amount of biological energy.
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Sexual Activity and Life Span, first reproduction may be delayed to maximize allocation of resources to growth earlier in life. Alternatively, if predation on adults is high, the age of first reproduction may be brought forward at the expense of growth.
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Role of Mitochondria in , Aging,Despite this apparent controversy, recent experimental evidence indicates that mitochondrial disorganization may be an important aspect of senescence in postmitotic cells, such as those found in the adult insect . (Miquel et al. 1980, Fleming et al. 1984).
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Structural Correlates of Aging in ,: Relevance to the Cell Differentiation, Rate-of-Living and Free and aging. Indeed, as noted elsewhere (Miquel and Fleming 1984), the cyto-logical homogeneity of the fruit fly is a great advantage for the elucidation of the fundamental mechanisms of aging, which are very hard to pinpoint in the complex mammalian tissues.
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Role of Steroids in Aging,l activities and histological appearances which can appropriately be described as senescence (Rockstein and Miquel 1973). A particularly appealing criterion for senescence in an insect would be an equivalent of menopause (Lockshin and Zimmerman 1983).
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