| 书目名称 | Innovations and Implementations of Computer Aided Drug Discovery Strategies in Rational Drug Design |
| 编辑 | Sanjeev Kumar Singh |
| 视频video | |
| 概述 | Highlights the role of phylogeny and molecular dynamics simulation in the drug discovery process.Presents in-silico models and enzymes that are involved in drug metabolism.Explores the role of recepto |
| 图书封面 |  |
| 描述 | This book presents various computer-aided drug discovery methods for the design and development of ligand and structure-based drug molecules. A wide variety of computational approaches are now being used in various stages of drug discovery and development, as well as in clinical studies. Yet, despite the rapid advances in computer software and hardware, combined with the exponential growth in the available biological information, there are many challenges that still need to be addressed, as this book shows. .In turn, it shares valuable insights into receptor-ligand interactions in connection with various biological functions and human diseases. The book discusses a wide range of phylogenetic methods and highlights the applications of Molecular Dynamics Simulation in the drug discovery process. It also explores the application of quantum mechanics in order to provide better accuracy when calculating protein-ligand binding interactions and predicting binding affinities. In closing, the book provides illustrative descriptions of major challenges associated with computer-aided drug discovery for the development of therapeutic drugs. Given its scope, it offers a valuable asset for life |
| 出版日期 | Book 2021 |
| 关键词 | Drug Design; CADD; Pharmacophore and QSAR; Molecular Docking; Molecular Dynamics Simulation; Rational Dru |
| 版次 | 1 |
| doi | https://doi.org/10.1007/978-981-15-8936-2 |
| isbn_softcover | 978-981-15-8938-6 |
| isbn_ebook | 978-981-15-8936-2 |
| copyright | Springer Nature Singapore Pte Ltd. 2021 |
发表于 2025-3-21 16:20:12
