| 书目名称 | Innate Immune Regulation and Cancer Immunotherapy |
| 编辑 | Rongfu Wang |
| 视频video | |
| 概述 | This book will discuss recent progress in innate immunity and Treg cells.This book will discuss the regulation of innate immunity through Toll-like receptor (TLR) signaling.Additionally, this book wil |
| 图书封面 |  |
| 描述 | .Innate and adaptive immunity play important roles in immunosurveillance and tumor destruction. However, increasing evidence suggests that tumor-infiltrating immune cells may have a dual function: inhibiting or promoting tumor growth and progression. Although regulatory T (Treg) cells induce immune tolerance by suppressing host immune responses against self- or non self-antigens, thus playing critical roles in preventing autoimmune diseases, they might inhibit antitumor immunity and promote tumor growth. Recent studies demonstrate that elevated proportions of Treg cells are present in various types of cancers and suppress antitumor immunity. Furthermore, tumor-specific Treg cells can inhibit immune responses only when they are exposed to antigens presented by tumor cells. Therefore, Treg cells at tumor sites have detrimental effects on immunotherapy directed to cancer. . |
| 出版日期 | Book 2012 |
| 关键词 | Myeloid-Derived Suppressive Cells; NKT Cells; Toll-Like Receptors; regulatory T cells; γδ T Cells |
| 版次 | 1 |
| doi | https://doi.org/10.1007/978-1-4419-9914-6 |
| isbn_softcover | 978-1-4899-8590-3 |
| isbn_ebook | 978-1-4419-9914-6 |
| copyright | Springer Science+Business Media, LLC 2012 |
发表于 2025-3-21 20:03:11
