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Titlebook: Inhibitors of Protein Biosynthesis; David Vázquez Book 1979 Springer-Verlag Berlin · Heidelberg 1979 biosynthesis.protein.synthesis

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Protein Synthesis and Translation Inhibitors,edly in the last fifteen years (Gale, 1963; Newton, 1965; Newton and Reynolds, 1966; Gottlieb and Shaw, 1967a; Vázquez and Monro, 1967; Weisblum and Davies, 1968; Pestka, 1971; Muñoz, García-Ferrandiz and Vázquez, 1972; Gale et al., 1972; Kaji, 1973; Vázquez, 1974; Corcoran and Hahn, 1975; Pestka, 1
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Termination,etermining the interaction of the release factors with the ribosome. A single release factor (RF) has been isolated from eukaryotic systems, GTP being required in the termination step (g.). On the other hand three release factors (RF-1, RF-2,and RF-3) have been obtained from bacterial systems; relea
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Miscellaneous Inhibitors of Translation,ynthesis in intact bacteria and bacterial cell-free systems (Wolf, 1973). The effect of the antibiotic is located on the 30S ribosomal subunit and inhibits polynucleotide-directed binding of f-Met-tRNA and Phe-tRNA to the ribosome. Since the antibiotic has not been studied in more resolved systems i
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Selectivity and Specificity Reconsidered,s appear to have narrower spectra of selectivity. Thus lincomycin is very active on ribosomes from gram-positive bacteria and moderately active on blue-green algae ribosomes, but has low activity on ribosomes from gram-negative bacteria in preventing peptide bond formation (Chang and Weisblum, 1967;
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Immunohistochemical Assessment of Differentiation and DNA Replication in Human Brain Tumorsged our way of thinking about neuro-oncogenesis (R. 1987a), and in surgical pathology, it has led to a significantly higher level of diagnostic accuracy (B. and R. 1984; K. et al. 1987). However, the application of immunocytochemical markers has not profoundly affected our view on the current classi
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Copper and the Mussel , is essential for the proper action of several enzymes (e.g., cytocrome oxidase, lysine oxidase and tyrosinase) and appears to function by forming strong complexes with proteins. In some molluscs copper is especially important because it is responsible for the oxygen binding haemolymph pigment haemo
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