| 书目名称 | Inhibitors of Cell Growth | | 编辑 | Alvaro Macieira-Coelho | | 视频video | | | 概述 | This book covers the whole range of inhibitors of cell growth, and considers therapeutic applications, development and structure-function relationships. | | 丛书名称 | Progress in Molecular and Subcellular Biology | | 图书封面 |  | | 描述 | The containment of cell growth is at the core of the homeostatic regulation of metazoans, and considerable progress has been made in the understanding of how this is achieved. Most knowledge comes from the isolation of molecu les with positive and negative regulatory effects on cell proliferation, and most emphasis so far has been on these molecules. Some of these molecules are already available for therapeutic purposes, and others look promising in this respect. This volume gives examples of such approaches. The understanding of the control of cell growth is also fundamental to grasp phylogenic and ontogenic development. Why organisms have developed increasingly sophisticated mechanisms that control their size and that of their organs, how different cells originate, some destined for renewal and repair, others for specialized functions in a postmitotic state or evolving through division, others like the germinal cells waiting for the signal to start another organism. There is one mechanism of growth containment, however, about which we know very little. It concerns the structural characteristics of the cell, i.e. the relationship between structure and function. How structure can | | 出版日期 | Book 1998 | | 关键词 | Activation; Krebs; RNA; angiogenesis; apoptosis; cancer; cell; cell cycle; cell division; interferon; oncogene | | 版次 | 1 | | doi | https://doi.org/10.1007/978-3-642-72149-6 | | isbn_softcover | 978-3-642-72151-9 | | isbn_ebook | 978-3-642-72149-6Series ISSN 0079-6484 Series E-ISSN 2197-8484 | | issn_series | 0079-6484 | | copyright | Springer-Verlag Berlin Heidelberg 1998 |
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发表于 2025-3-21 16:57:46
