书目名称 | Inguinal Hernia: Pathophysiology and Genesis of the Disease | 编辑 | Giuseppe Amato | 视频video | | 概述 | Highlights the inguinal region physiopathology based on histological evidences.Provides for an evidence-based rationalization of the surgical treatment.Offers an original interpretation of‘ frequent b | 图书封面 |  | 描述 | .This book aims at filling a gap in relation to the pathophysiology of the inguinal region and the genesis of groin protrusions. While inguinal hernia is a widespread disease and hernia repair accounts for the most frequently performed surgical procedure, these two aspects have been unsatisfactorily investigated, so that to date there is no shared hypothesis on how visceral protrusion through inguinal barrier occur. Exact knowledge on the pathogenesis is fundamental for adequately managing a disease, otherwise all curative approaches would not be evidence-based, but merely empirically identified and with uncertain outcomes carried out. Moreover, in absence of pathogenetic certainty, formulating guidelines simply results in an unjustified methodology harbinger of polemics and controversies. Previous studies concerning the pathogenesis of inguinal protrusions were mainly focused on the detection of biochemical changes, mostly related to collagen chains, metalloproteinase and similar elements. Nevertheless, despite decades of researches, a sure relationship between these ultrastructural modifications and visceral protrusion has not been proven. On the contrary, over the years very | 出版日期 | Book 2022 | 关键词 | Chronic degenerative damage; Septum inguinalis; Pathogenesis of inguinal protrusions; Histology of ingu | 版次 | 1 | doi | https://doi.org/10.1007/978-3-030-95224-2 | isbn_softcover | 978-3-030-95226-6 | isbn_ebook | 978-3-030-95224-2 | copyright | The Editor(s) (if applicable) and The Author(s), under exclusive license to Springer Nature Switzer |
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