Titlebook: Inflammatory Disorders of the Nervous System; Pathogenesis, Immuno Alireza Minagar,J. Steven Alexander Book 2017Latest edition Springer Int

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Emerging Roles of Endothelial Cells in Multiple Sclerosis Pathophysiology and Therapy,veral types of intercellular junctions which isolate the circulation from the brain as the functional neuro- and gliovascular units of the BBB. In health, the BBB generally isolates the brain parenchyma from immune cells and blood-borne neurotransmitters (glutamate, norepinephrine, serotonin) contro

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Multiple Sclerosis: Clinical Features, Immunopathogenesis, and Treatment,oxysmal manifestations. These symptoms necessitate a myriad of treatment approaches tailored to individual patient needs. A boom in the development of disease-modifying therapies for MS has resulted in 14 currently FDA-approved medications for relapsing-remitting MS in 2016 compared to just a handfu

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Neurosarcoidosis: Clinical Features, Pathogenesis, and Management,ly, the treatment is based on chronic immunosuppression utilizing TNF-α antagonists, corticosteroids, and a number of cytotoxic medications. Symptomatic treatments of the neurologic complications of neurosarcoidosis involve multiple treatment teams and use of various medications.

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Immunopathogenesis and Treatment of Guillain-Barre Syndrome and Chronic Inflammatory Demyelinating there are relapses. On the other hand, maintenance treatment with the aforementioned treatment modalities, as well as corticosteroids or other immunosuppressants, is frequently needed in CIDP patients. Further advances in the understanding of immunopathogenesis of these diseases will likely result

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Central Nervous System Vasculitis: Immunopathogenesis, Clinical Aspects, and Treatment Options,nt immunosuppressive therapy, as well as the choice and dosing of therapy, along with the duration, are important determinants of outcome in central nervous vasculitis. We hope to provide updated information toward these goals in this chapter.