| 书目名称 | Inflammatory Diseases and Copper | | 副标题 | The Metabolic and Th | | 编辑 | John R. J. Sorenson | | 视频video | http://file.papertrans.cn/465/464720/464720.mp4 | | 丛书名称 | Experimental Biology and Medicine | | 图书封面 |  | | 描述 | In 1928, it was discovered that copper was essential for normal human metabolism. A decade later, in 1938, it was observed that patients with rheu matoid arthritis exhibited a higher than normal serum copper concentration that returned to normal with remission of this disease. Thirteen years later, it was found that copper complexes were effective in treating arthritic dis eases. The first report that copper complexes had antiinflammatory activity in an animal model of inflammation appeared twenty-two years after the dis covery of essentiality. In 1976, it was suggested that the active forms of the antiarthritic drugs are their copper complexes formed in vivo. This sugges tion has been confirmed and extended in the interim in over 200 recent publications. Individual biomedical scientists from many countries who have published in these areas recently saw a need for a meeting to exchange current re supporting new hypotheses. We search results and discuss the evidence met on the University of Arkansas Medical Sciences campus in Little Rock, Arkansas, August 10-13, 1981. Participants came from Australia, England, France, Germany, Israel, Italy, The Netherlands, Norway, Poland, Sco | | 出版日期 | Book 1982 | | 关键词 | Amino acid; Arthritis; Lipid; Oxidation; inflammation; metabolism; protein; rheumatic diseases; rheumatoid a | | 版次 | 1 | | doi | https://doi.org/10.1007/978-1-4612-5829-2 | | isbn_softcover | 978-1-4612-5831-5 | | isbn_ebook | 978-1-4612-5829-2 | | copyright | The Humana Press Inc. 1982 |
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