Titlebook: Inflammation in the Pathogenesis of Chronic Diseases; The COX-2 Controvers Randall E. Harris (Director),R. Bittman,P. Zwickl Book 2007 Spri

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Role of COX-2 in Inflammatory and Degenerative Brain Diseases-expression has been associated with neurotoxiticy in acute conditions, such as hypoxia/ischemia and seizures, as well as in inflammatory chronic diseases, including Creutzfeldt-Jakob disease (CJD) and Alzheimer’s disease (AD). However, the role played by COX-2 in neurodegenerative diseases is still

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Cardiovascular Effects of the Selective Cyclooxygenase-2 Inhibitorsselective inhibitors before making therapeutic decisions for the management of chronic arthritis. In clinical practice, the majority of patients with moderate to severe arthritis who might benefit from NSAID or COX-2 therapy are likely to be elderly and, therefore, at higher risk for gastrointestina

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COX-2 Inhibitors And Cardiovascular Riskng knowledge of micro-cellular structure and function. However, theoretical concerns about potentially pro-thrombotic effects of selective COX-2 inhibitors coupled with observations of increased cardiovascular risk have produced significant consternation and lead to the withdrawal of two of these ag

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