Titlebook: Inflammation in Parkinson‘s Disease; Scientific and Clini Madhavi Thomas Book 2014 Springer International Publishing Switzerland 2014 Biolo

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,Clinical Aspects of Inflammation in Parkinson’s Disease,r investigation. Current evidence shows chronic inflammation is now seen as a plausible mechanism of neurodegeneration in PD. Various biological markers such as cytokines, antibodies to alpha-synuclein, and peripheral T-cell changes have been shown in literature. Furthermore, comorbidity studies, ge

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,The Role of Astrocytes in Parkinson’s Disease,trocytic dysfunction may compromise the efficacy of L-DOPA therapy. These unique astrocytic responses to the disease process and current main therapy support the concept that astrocytes play a critical, under-recognized role in the initiation, progression, and treatment response of patients with Par

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,Cell Culture Models of Inflammation in Parkinson’s Disease,ear exactly how these cell culture models relate to the progression of PD, they offer an excellent model for understanding the effects of oxidative stress, cytokines, prostaglandins, and other inflammatory mediators on DA neurons, NeuN. neurons, astrocytes, and other cells within the SN, as well as

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Book 2014 and students interested in Parkinson‘s Disease are provided with a comprehensive view of translational research methods and an insight needed for developing future therapies aimed at disease modulation..