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Titlebook: Inflammation and Lung Cancer; Steven M. Dubinett Book 2015 Springer Science+Business Media New York 2015 Inflammation.Lung cancer.Micro-RN

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书目名称Inflammation and Lung Cancer
编辑Steven M. Dubinett
视频video
概述Presents the inflammatory tumor microenvironment in lung cancer.Explores inflammation and how it affects epigenetic events in lung cancer.Discusses the connection between chronic overexpression and de
图书封面Titlebook: Inflammation and Lung Cancer;  Steven M. Dubinett Book 2015 Springer Science+Business Media New York 2015 Inflammation.Lung cancer.Micro-RN
描述In recent years there have been various discoveries connecting inflammation and lung cancer and clearly there is growing interest in this area of cancer research. The link between unresolved inflammation and cancer has been well established with estimates that 15% of cancer deaths are inflammation‐related. Evidence for this link includes the following: a) some inflammatory diseases are associated with increased risk of cancer development; b) inflammatory mediators are present surrounding and within most tumors; c) overexpression of inflammatory cytokines increases cancer development and progression in murine studies; d) inhibition of inflammatory mediators decreases cancer development and progression; and e) the use of non‐steroidal anti‐inflammatory drugs (NSAIDs) has been found to decrease cancer incidence and delay progression. The volume will present aspects of the inflammatory tumor microenvironment (TME), its many roles in tumor progression and metastasis, including creation of a hypoxic environment, increased angiogenesis and invasion, changes in expression of micro‐RNAs (miRNAs) and an increase in a stem cell phenotype. The book will also cover the mechanisms of inflammator
出版日期Book 2015
关键词Inflammation; Lung cancer; Micro-RNAs; Non-small cell; Tumor microenvironment
版次1
doihttps://doi.org/10.1007/978-1-4939-2724-1
isbn_softcover978-1-4939-4511-5
isbn_ebook978-1-4939-2724-1
copyrightSpringer Science+Business Media New York 2015
The information of publication is updating

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978-1-4939-4511-5Springer Science+Business Media New York 2015
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Sherven Sharma PhD,Siwen Hu-Lieskovan MD, PhD,Steven M. Dubinett MD,Jay Moon Lee MDe 1960s, typically in the fundamental memoir "The Non-Linear Field Theories of Mechanics" by Truesdell and Noll. The theoretical aspect of constitutive theories for materials in general has been carefully developed in mathemati­ cal clarity - from general kinematics, balance equations, material obje
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e 1960s, typically in the fundamental memoir "The Non-Linear Field Theories of Mechanics" by Truesdell and Noll. The theoretical aspect of constitutive theories for materials in general has been carefully developed in mathemati­ cal clarity - from general kinematics, balance equations, material obje
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Inflammation and Lung Cancer: The Relationship to Chronic Obstructive Pulmonary Disease,dence even after correcting for cigarette smoke consumption. The mechanistic explanations for this epidemiologic link remain poorly understood as the two disease processes are seemingly polar opposites. However, there are key shared pathologic mechanisms that may link COPD and lung cancer, and infla
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,Inflammation and Lung Cancer: The Role of Epithelial–Mesenchymal Transition, Physiologic EMT is an essential part of normal embryonic development and an adult organism’s ability to overcome acute injury. However, chronic injury and inflammation can yield dysregulated or pathologic EMT that drives organ fibrosis and cancer development. In this chapter, we review seminal work
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