书目名称 | Inflammation and Lung Cancer | 编辑 | Steven M. Dubinett | 视频video | | 概述 | Presents the inflammatory tumor microenvironment in lung cancer.Explores inflammation and how it affects epigenetic events in lung cancer.Discusses the connection between chronic overexpression and de | 图书封面 |  | 描述 | In recent years there have been various discoveries connecting inflammation and lung cancer and clearly there is growing interest in this area of cancer research. The link between unresolved inflammation and cancer has been well established with estimates that 15% of cancer deaths are inflammation‐related. Evidence for this link includes the following: a) some inflammatory diseases are associated with increased risk of cancer development; b) inflammatory mediators are present surrounding and within most tumors; c) overexpression of inflammatory cytokines increases cancer development and progression in murine studies; d) inhibition of inflammatory mediators decreases cancer development and progression; and e) the use of non‐steroidal anti‐inflammatory drugs (NSAIDs) has been found to decrease cancer incidence and delay progression. The volume will present aspects of the inflammatory tumor microenvironment (TME), its many roles in tumor progression and metastasis, including creation of a hypoxic environment, increased angiogenesis and invasion, changes in expression of micro‐RNAs (miRNAs) and an increase in a stem cell phenotype. The book will also cover the mechanisms of inflammator | 出版日期 | Book 2015 | 关键词 | Inflammation; Lung cancer; Micro-RNAs; Non-small cell; Tumor microenvironment | 版次 | 1 | doi | https://doi.org/10.1007/978-1-4939-2724-1 | isbn_softcover | 978-1-4939-4511-5 | isbn_ebook | 978-1-4939-2724-1 | copyright | Springer Science+Business Media New York 2015 |
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