Titlebook: In vivo Models of HIV Disease and Control; Herman Friedman,Steven Specter,Mauro Bendinelli Book 2006 Springer-Verlag US 2006 AIDS.AIDS vac

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Mauro Pistello emergency response plans. In addition to measures taken to reduce economical and human losses, an environmental dimension is required in these plans to control environmental pollution and lessen possible adverse effects on both ecosystems and human health, which in the long term may cost much more

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Historical Perspective,ost attention was directed at the cancer-inducing role of the oncogenic retroviruses and, in particular, their genetic transmission in inbred mice as endogenous proviral DNA. Only since the onset of the AIDS pandemic in 1981 has interest centered on the nononcogenic, particularly immunosuppressive p

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SIV as a Model for AIDS Pathogenesis Studies,ered derivatives, such as chimeras between HIV-1 and SIV (SHIV), are thus indispensable for the proof-of-concept testing and the definition of potential correlates of immune protection in HIV-vaccine design. SIVinfected macaques are also the animal model system of choice to perform etiopathological

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SIV Infection of Macaques as a Model for AIDS Drug Studies,s during the viral replication cycle, the main antiviral drugs that have been approved or are being developed belong to several groups: inhibitors of attachment, fusion, reverse transcriptase (RT), integrase or protease (Figure 1). During recent years, combination therapy of these compounds, so-call

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